Combine cooked spaghetti squash, cream cheese, shredded chicken and hot sauce in a large glass bowl. Microwave mixture for 30 seconds, then stir. Microwave another 30 seconds and stir.
Add shredded cheddar cheese and 1 teaspoon powdered ranch dressing. Stir to combine.
Transfer to a casserole dish. Bake for 25-30 minutes until mixture is heated through and cheese is melted.